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簡(jiǎn)要描述:The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. The protein has an N-terminal PHD finger and a central Jumonji C domain. This gene is thought to function as a transcription activator. Defects in this gene are a cause of syndromic X-linked Siderius type intellectual disability (MRXSSD) and over-expression of
產(chǎn)品型號(hào):bsm-60652R
廠商性質(zhì):生產(chǎn)廠家
更新時(shí)間:2025-03-01
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