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  • bsm-63281R磷酸化表皮生長因子受體重組兔單抗

    The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript var

    更新時間:2025-03-05
    型號:bsm-63281R
    廠商性質:生產廠家
    瀏覽量:48
  • bsm-63280R磷酸化血小板源性生長因子受體B重組兔單抗

    This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimula

    更新時間:2025-03-05
    型號:bsm-63280R
    廠商性質:生產廠家
    瀏覽量:45
  • bsm-63279R磷酸化干擾素誘導的雙鏈RNA活化蛋白激酶重組兔單抗

    PKR is an interferon-inducible serine/threonine specific protein kinase. It is widely expressed in eukaryotic organisms and activated by double stranded RNA. Activation of PKR by dsRNAs leads to autophosphorylation at multiple sites. Phosphorylation of Thr446 and Thr451 in the PKR activation loop is required in vivo and in vitro for high level kinase activity. PKR phosphorylates its natural substrate, the alpha subunit of eukaryotic protein synthesis initiation factor 2 (EIF2 alpha), leading

    更新時間:2025-03-05
    型號:bsm-63279R
    廠商性質:生產廠家
    瀏覽量:38
  • bsm-63278R磷酸化細胞質膜微囊蛋白-1重組兔單抗

    The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins

    更新時間:2025-03-05
    型號:bsm-63278R
    廠商性質:生產廠家
    瀏覽量:51
  • bsm-63277R磷酸化eIF4E結合蛋白重組兔單抗

    This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting

    更新時間:2025-03-05
    型號:bsm-63277R
    廠商性質:生產廠家
    瀏覽量:45
  • bsm-63276R磷酸化粘著斑激酶重組兔單抗

    Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. [SUBCELLULAR

    更新時間:2025-03-05
    型號:bsm-63276R
    廠商性質:生產廠家
    瀏覽量:40
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